Pathogenic anti-desmoglein MAbs show variable ELISA activity because of preferential binding of mature versus proprotein isoforms of desmoglein 3

J Invest Dermatol. 2009 Sep;129(9):2309-12. doi: 10.1038/jid.2009.41. Epub 2009 Mar 12.
No abstract available

Publication types

  • Comparative Study
  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antibodies, Monoclonal / immunology*
  • Desmoglein 3 / immunology*
  • Enzyme-Linked Immunosorbent Assay*
  • Epitopes
  • Humans
  • Mice
  • Pemphigus / immunology*
  • Protein Isoforms
  • Protein Precursors / immunology*

Substances

  • Antibodies, Monoclonal
  • Desmoglein 3
  • Epitopes
  • Protein Isoforms
  • Protein Precursors