Abstract
Progressive dementia developed during a 15-month period in a 56-year-old woman with serologically and clinically documented primary Sjögren's syndrome. Findings from magnetic resonance imaging and angiography were normal, but a brain biopsy disclosed perivascular lymphocytic inflammation in leptomeningeal and parenchymal vessels. Treatment with high-dose corticosteroids produced rapid and nearly complete resolution of the dementia.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Alzheimer Disease / diagnosis
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Dementia / diagnosis
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Dementia / drug therapy
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Dementia / etiology*
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Diagnostic Errors
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Female
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Hallucinations / drug therapy
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Hallucinations / etiology
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Humans
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Meningoencephalitis / drug therapy
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Meningoencephalitis / etiology*
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Middle Aged
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Paranoid Behavior / drug therapy
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Paranoid Behavior / etiology
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Prednisone / therapeutic use*
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Psychological Tests
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Sjogren's Syndrome / complications*
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Sjogren's Syndrome / drug therapy