Abstract
Hepatocellular carcinoma (HCC) is one of the commonest cancers worldwide, particularly in parts of the developing world, and is increasing in incidence. This article reviews the current modalities employed for the diagnosis of HCC, including serum markers, radiological techniques and histological evaluation, and summarises international guidelines for the diagnostic approach to HCC.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Antigens, Neoplasm / blood
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Biomarkers / metabolism
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Biomarkers, Tumor / blood
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Carcinoma, Hepatocellular / diagnosis*
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Carcinoma, Hepatocellular / diagnostic imaging
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Carcinoma, Hepatocellular / epidemiology
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Carcinoma, Hepatocellular / pathology
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Hepatitis C / complications
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Hepatocyte Growth Factor / blood
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Humans
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Liver Cirrhosis / complications
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Liver Neoplasms / diagnosis*
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Liver Neoplasms / diagnostic imaging
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Liver Neoplasms / epidemiology
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Liver Neoplasms / pathology
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Membrane Proteins / blood
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Neoplasm Staging
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Protein Precursors / metabolism
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Proteomics
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Prothrombin / metabolism
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Radiography
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Risk Factors
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Serpins / blood
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Vascular Endothelial Growth Factor A / blood
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alpha-Fetoproteins / metabolism
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alpha-L-Fucosidase / blood
Substances
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Antigens, Neoplasm
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Biomarkers
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Biomarkers, Tumor
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GOLM1 protein, human
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Membrane Proteins
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Protein Precursors
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Serpins
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Vascular Endothelial Growth Factor A
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alpha-Fetoproteins
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squamous cell carcinoma-related antigen
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acarboxyprothrombin
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Hepatocyte Growth Factor
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Prothrombin
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alpha-L-Fucosidase