[Study on effect of promoting blood circulation drugs components in treating unstable angina in patients with blood stasis inflammatory levels]

Zhongguo Zhong Yao Za Zhi. 2008 Dec;33(24):2950-3.
[Article in Chinese]

Abstract

Objective: To discussion the effects of Huoxue components of effective drug in treating unstable angina in patients with blood stasis WBC (WBC), C-reactive protein (CRP), interleukin-6 (IL-6) and tumor necrosis factor alpha (TNF-alpha).

Method: one hundred and twenty cases of unstable angina were randomly divided into the conventional therapy group, component compatibility group, Pieces group and Xuesaitong group 4 groups, each with 30 cases. Observation of patients before and after treatment of clinical efficacy, blood lipid indicators and the indicators changes.

Result: Component compatibility group after treatment clinical marked improvement in conditions, and the WBC, CRP, IL-6 and TNF-alpha, TC, TG levels lower than before treatment, there were significant differences (P < 0.05), and lower than the other three groups After treatment (P < 0.05). And HDL-C after treatment than before treatment increased, there were significant differences (P < 0. 05).

Conclusion: Huoxue-effective component compatibility can be effective treatment of unstable angina blood stasis, and could inhibit the inflammatory level.

Publication types

  • English Abstract
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Angina, Unstable / blood
  • Angina, Unstable / drug therapy*
  • Angina, Unstable / immunology*
  • Blood Circulation / drug effects*
  • C-Reactive Protein / immunology
  • Cardiotonic Agents / administration & dosage*
  • Drugs, Chinese Herbal / administration & dosage*
  • Female
  • Humans
  • Interleukin-6 / blood
  • Interleukin-6 / immunology
  • Leukocytes / drug effects
  • Male
  • Middle Aged
  • Tumor Necrosis Factor-alpha / blood
  • Tumor Necrosis Factor-alpha / immunology

Substances

  • Cardiotonic Agents
  • Drugs, Chinese Herbal
  • Interleukin-6
  • Tumor Necrosis Factor-alpha
  • C-Reactive Protein