Serum retinol binding protein 4 in patients with familial partial lipodystrophy

Amélio F Godoy-Matos; Rodrigo O Moreira; Renata MacDowell; Izidro Bendet; Patrícia B Mory; Regina S Moises

doi:10.1016/j.clinbiochem.2009.03.006

Serum retinol binding protein 4 in patients with familial partial lipodystrophy

Clin Biochem. 2009 Jul;42(10-11):1183-6. doi: 10.1016/j.clinbiochem.2009.03.006. Epub 2009 Mar 18.

Authors

Amélio F Godoy-Matos¹, Rodrigo O Moreira, Renata MacDowell, Izidro Bendet, Patrícia B Mory, Regina S Moises

Affiliation

¹ Instituto Estadual de Diabetes e Endocrinologia do Rio de Janeiro, Rio de Janeiro, Brasil. [email protected]

PMID: 19303000
DOI: 10.1016/j.clinbiochem.2009.03.006

Abstract

Objective: To determine Retinol Binding Protein 4 (RBP4) levels in patients with Familial Partial Lipodystrophy (FPLD).

Methods: Ten patients with FPLD and a control group (9 patients) were selected to participate in the study.

Results: RBP4-log levels were lower in patients with FPLD in comparison to control group (1.52 +/- 0.32 vs 1.84+/-0.25, p=0.029). A statistical trend was observed between Waist-to-Hip Ratio and RBP4-log (r=-0.44, p=0.054).

Conclusion: RBP4 levels are decreased in FPLD.

MeSH terms

Adult
Case-Control Studies
Female
Humans
Lipodystrophy, Familial Partial / blood*
Retinol-Binding Proteins, Plasma / metabolism*
Waist-Hip Ratio

Substances

RBP4 protein, human
Retinol-Binding Proteins, Plasma