A gate keeper for axonal transport

Shaohua Xiao; Lily Yeh Jan

doi:10.1016/j.cell.2009.03.003

A gate keeper for axonal transport

Cell. 2009 Mar 20;136(6):996-8. doi: 10.1016/j.cell.2009.03.003.

Authors

Shaohua Xiao¹, Lily Yeh Jan

Affiliation

¹ Department of Physiology, University of California, San Francisco, CA 94143, USA.

PMID: 19303842
DOI: 10.1016/j.cell.2009.03.003

Abstract

The axon and dendritic arbor of neurons require different sets of membrane proteins to carry out their functions. In this issue, Song et al. (2009) describe how a cytoplasmic diffusion barrier in the axon initial segment of rat hippocampal neurons ensures that only axonal (and not dendritic) membrane proteins enter the axon.

Publication types

Comment
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Axonal Transport*
Cytoplasm / metabolism*
Hippocampus / metabolism
Neurons / metabolism
Rats

Abstract

Publication types

MeSH terms

Grants and funding