Infernal 1.0: inference of RNA alignments

Bioinformatics. 2009 May 15;25(10):1335-7. doi: 10.1093/bioinformatics/btp157. Epub 2009 Mar 23.

Abstract

Summary: INFERNAL builds consensus RNA secondary structure profiles called covariance models (CMs), and uses them to search nucleic acid sequence databases for homologous RNAs, or to create new sequence- and structure-based multiple sequence alignments.

Availability: Source code, documentation and benchmark downloadable from http://infernal.janelia.org. INFERNAL is freely licensed under the GNU GPLv3 and should be portable to any POSIX-compliant operating system, including Linux and Mac OS/X.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Databases, Nucleic Acid
  • Nucleic Acid Conformation
  • RNA / chemistry*
  • Sequence Alignment / methods*
  • Sequence Analysis, RNA*
  • Software*

Substances

  • RNA