Multilevel surgery in patients with rapid eye movement-related obstructive sleep apnea

Otolaryngol Head Neck Surg. 2009 Apr;140(4):536-41. doi: 10.1016/j.otohns.2009.01.006.

Abstract

Objective: To compare the anatomic features and the results of a multilevel surgery in patients with rapid eye movement-related obstructive sleep apnea (REM OSA) and non-REM OSA.

Study design: Cohort study of 90 consecutive mild or moderate OSA patients.

Subjects and methods: The apnea-hypopnea index (AHI) was also calculated during REM sleep (AHI(REM)) and during non-REM sleep (AHI(NREM)), and patients were classified as having REM OSA if their AHI(REM)/AHI(NREM) ratio was >2, otherwise they were classified as non-REM OSA patients. All patients underwent concurrent uvulopalatopharyngoplasty and a radiofrequency tongue base reduction procedure.

Results: A total of 31.1 percent patients were classified as REM OSA and 68.9 percent patients as non-REM OSA. There were no differences in the anatomical features between two groups. However, the AHI, HI, and arousal index were significantly higher in the non-REM OSA group than in the REM OSA group. When a successful outcome was defined as a postoperative AHI <20 with at least a 50 percent reduction from the preoperative level, 50 percent of the patients with REM OSA and 35.5 percent of the patients with non-REM OSA met the criteria for a successful outcome.

Conclusions: REM OSA patients had milder obstructive sleep apnea, and multilevel surgery might be more effective in REM OSA patients.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Body Size
  • Cohort Studies
  • Female
  • Humans
  • Male
  • Middle Aged
  • Otorhinolaryngologic Surgical Procedures*
  • Polysomnography
  • Retrospective Studies
  • Sleep Apnea, Obstructive / pathology
  • Sleep Apnea, Obstructive / physiopathology*
  • Sleep Apnea, Obstructive / surgery*
  • Sleep, REM*
  • Treatment Outcome