Abstract
Live-cell imaging studies aided by mathematical modeling have provided unprecedented insight into assembly mechanisms of multiprotein complexes that control genome function. Such studies have unveiled emerging properties of chromatin-associated systems involved in DNA repair and transcription.
Publication types
-
Research Support, Non-U.S. Gov't
-
Review
MeSH terms
-
Chromatin / chemistry
-
Chromatin / metabolism*
-
DNA Repair
-
DNA-Binding Proteins / chemistry
-
DNA-Binding Proteins / metabolism*
-
DNA-Binding Proteins / physiology
-
Genome*
-
Kinetics
-
Models, Biological
-
Models, Molecular
-
Nuclear Proteins / chemistry
-
Nuclear Proteins / metabolism*
-
Nuclear Proteins / physiology
-
Transcription, Genetic
Substances
-
Chromatin
-
DNA-Binding Proteins
-
Nuclear Proteins