Fundus autofluorescence in cone dystrophy

Doc Ophthalmol. 2009 Oct;119(2):141-4. doi: 10.1007/s10633-009-9172-y. Epub 2009 Apr 2.

Abstract

Purpose: To describe fundus autofluorescence (FAF) finding in a case of cone dystrophy.

Methods: Interventional case report.

Results: A 23-year-old woman presented with increasing photophobia and decreasing vision in both eyes for 2 years. Fundus examination showed several drusen-like dots. FAF revealed hyper-autofluorescence in the foveola. Electroretinogram (ERG) demonstrated a pure "cone" dystrophy.

Conclusion: Hyper-autofluorescence in the foveola is a non-specific manifestation of photoreceptor-retinal pigment epithelium dysfunction. ERG studies are essential for accurate diagnosis.

Publication types

  • Case Reports
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Color Vision Defects / diagnosis*
  • Electroretinography
  • Female
  • Fluorescence*
  • Fundus Oculi
  • Humans
  • Photophobia / diagnosis
  • Retinal Cone Photoreceptor Cells / pathology*
  • Retinal Degeneration / diagnosis*
  • Tomography, Optical Coherence
  • Young Adult