Ethnicity, socioeconomic status, and attainment of clinical practice guideline standards in dialysis patients in the United kingdom

Clin J Am Soc Nephrol. 2009 May;4(5):979-87. doi: 10.2215/CJN.06311208. Epub 2009 Apr 8.

Abstract

Background and objectives: The role of socioeconomic status (SES) and its contribution to ethnic differences in standards attainment among dialysis patients is not known.

Design, setting, participants, & measurements: We examined associations between area- level SES (Townsend index) and ethnicity (white, black, South Asian) and standards attainment in 14,117 incident dialysis patients (1997-2004) in the UK.

Results: Deprived patients were less likely to achieve hemoglobin (Hb) > or = 10 g/dl (trend P < 0.001) but not after controlling for patient and center characteristics (trend P = 0.1). There was no association with hemodialysis dose and parathyroid hormone (PTH) standard but deprived patients had better attainment of phosphate (PO4) <5.6 mg/dl, calcium (Ca) and Calcium-phosphate (CaPO4) standard (e.g., most deprived versus least deprived adjusted odds ratio [OR] 1.25, 95% confidence intervals [CI] 1.12, 1.38). There was no association with SES using a lower limit for PO4 (3.5 - 5.5 mg/dl). Compared with Whites, Blacks had lower attainment of Hb (adjusted OR 0.57, 95% CI 0.45, 0.71) and PTH standards (adjusted OR 0.27, 95% CI 0.22, 0.33) but better attainment of PO4 and CaPO4, while South Asians experienced better or comparable outcomes for most standards except Ca and PTH.

Conclusions: There was no evidence of socioeconomic inequity in standards attainment or a consistent pattern of inequity by ethnic group. The lower attainment of some standards in ethnic minorities may reflect biologic differences rather than ethnicity-related inequity of care.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Asian People / statistics & numerical data
  • Black People / statistics & numerical data
  • Cohort Studies
  • Female
  • Guideline Adherence / statistics & numerical data*
  • Health Services Accessibility
  • Hemoglobins / metabolism
  • Humans
  • Kidney Failure, Chronic / ethnology*
  • Kidney Failure, Chronic / therapy*
  • Male
  • Middle Aged
  • Parathyroid Hormone / blood
  • Practice Guidelines as Topic
  • Quality of Health Care*
  • Registries / statistics & numerical data
  • Renal Dialysis / standards*
  • Renal Dialysis / statistics & numerical data*
  • Social Class
  • United Kingdom / epidemiology
  • White People / statistics & numerical data
  • Young Adult

Substances

  • Hemoglobins
  • PTH protein, human
  • Parathyroid Hormone