Pouch design and long-term functional outcome after ileal pouch-anal anastomosis

Br J Surg. 2009 May;96(5):527-32. doi: 10.1002/bjs.6590.

Abstract

Background: Functional outcome is of utmost importance after ileal pouch-anal anastomosis. Although pouch design and construction of the anastomosis are known technical determinants of function, there are few long-term results. This retrospective study evaluated functional outcome for two different pouch designs, and for handsewn versus stapled pouch-anal anastomoses.

Methods: The analysis included 412 patients who had either a J or K pouch (double-folded J pouch), of whom 123 had a J pouch (96 handsewn and 27 stapled) and 289 had a K pouch (95 handsewn and 194 stapled). Functional outcome was evaluated by a mailed questionnaire to achieve an Oresland score (0 to 15; 15 worst).

Results: Mean functional scores were 6.1 for J pouches and 4.9 for K pouches (P < 0.001). Regression analysis showed that reservoir design and age at surgery were predictors of functional outcome (P < 0.001). A higher proportion of patients with a J pouch and handsewn anastomosis than with a K pouch and stapled anastomosis had a score of 8 or more, a level previously demonstrated to impact negatively on quality of life (32 versus 16 per cent; P = 0.006).

Conclusion: The K pouch was associated with a better long-term functional outcome than the J pouch in this patient population.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Anal Canal / surgery*
  • Anastomosis, Surgical
  • Colonic Diseases / physiopathology
  • Colonic Diseases / surgery*
  • Colonic Pouches / physiology*
  • Defecation / physiology
  • Fecal Incontinence / etiology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Postoperative Complications / etiology
  • Prosthesis Design
  • Surgical Stapling*
  • Suture Techniques*
  • Treatment Outcome
  • Young Adult