First gene cassettes of integrons as targets in finding adaptive genes in metagenomes

Appl Environ Microbiol. 2009 Jun;75(11):3823-5. doi: 10.1128/AEM.02394-08. Epub 2009 Apr 10.

Abstract

The first gene cassettes of integrons are involved in the last adaptation response to changing conditions and are also the most expressed. We propose a rapid method for the selection of clones carrying an integron first gene cassette that is useful for finding adaptive genes in environmental metagenomic libraries.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adaptation, Biological*
  • Bacteria / genetics*
  • DNA, Bacterial / chemistry
  • DNA, Bacterial / genetics
  • Integrons*
  • Molecular Sequence Data
  • Sequence Analysis, DNA

Substances

  • DNA, Bacterial

Associated data

  • GENBANK/FM210532
  • GENBANK/FM210533
  • GENBANK/FM210534
  • GENBANK/FM210535
  • GENBANK/FM210665
  • GENBANK/FM210666
  • GENBANK/FM210667
  • GENBANK/FM210668
  • GENBANK/FM210669
  • GENBANK/FM210670
  • GENBANK/FM210671
  • GENBANK/FM210672
  • GENBANK/FM210673
  • GENBANK/FM210674
  • GENBANK/FM210675
  • GENBANK/FM210676
  • GENBANK/FM210677
  • GENBANK/FM210678
  • GENBANK/FM210679