First peak insulin release after intravenous glucose and arginine is maintained for up to 3 years after segmental pancreas transplantation

Diabetologia. 1991 Aug:34 Suppl 1:S53-6. doi: 10.1007/BF00587620.

Abstract

In this study we have investigated blood glucose and serum free insulin response to glucose and to arginine orally or intravenously, 3 months and 3 years after a successful segmental, neoprene-injected, pancreas transplantation. Serum insulin responses to different secretagogues were normal 3 months after transplantation; they remained normal up to 3 years after transplantation.

MeSH terms

  • Arginine*
  • Blood Glucose / metabolism*
  • Diabetes Mellitus, Type 1 / physiopathology
  • Diabetes Mellitus, Type 1 / surgery*
  • Diabetic Nephropathies / surgery
  • Follow-Up Studies
  • Glucose Tolerance Test
  • Humans
  • Insulin / blood
  • Insulin / metabolism*
  • Insulin Secretion
  • Kidney Transplantation / physiology
  • Pancreas Transplantation / physiology*

Substances

  • Blood Glucose
  • Insulin
  • Arginine