Abstract
In four of five HIV-1 and HIV-2 dually infected patients treated with efavirenz-based therapy, viral load was undetectable for HIV-1 only, with limited increase in CD4+ counts. Both viral loads were undetectable and CD4+ counts increased in one patient treated with protease inhibitor regimen. Specific guidelines for treating HIV-dually infected patients are needed that should avoid the use of non-nucleoside reverse transcriptase inhibitors.
Publication types
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Case Reports
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Adult
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Anti-HIV Agents / pharmacology
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Anti-HIV Agents / therapeutic use*
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CD4 Lymphocyte Count
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Cote d'Ivoire
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Enzyme-Linked Immunosorbent Assay
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Female
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HIV Infections / drug therapy*
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HIV Infections / immunology
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HIV Infections / virology*
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HIV Protease Inhibitors / pharmacology
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HIV Protease Inhibitors / therapeutic use
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HIV-1 / drug effects*
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HIV-2 / drug effects*
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Humans
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Male
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Middle Aged
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Polymerase Chain Reaction
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Reverse Transcriptase Inhibitors / pharmacology
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Reverse Transcriptase Inhibitors / therapeutic use
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Viral Load
Substances
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Anti-HIV Agents
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HIV Protease Inhibitors
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Reverse Transcriptase Inhibitors