The prognostic role of uterine artery Doppler studies in patients with late-onset preeclampsia

Am J Obstet Gynecol. 2009 Jul;201(1):36.e1-5. doi: 10.1016/j.ajog.2009.02.024. Epub 2009 Apr 19.

Abstract

Objective: To evaluate the usefulness of uterine artery Doppler in the prediction of outcome in patients with late-onset preeclampsia.

Study design: Patients with late-onset preeclampsia underwent Doppler interrogation of the uterine arteries. Patients with abnormal uterine artery Doppler were compared with those who had a normal uterine artery Doppler.

Results: Ninety-nine patients were included in the study group. Abnormal uterine artery Doppler group presented significantly lower gestational age at admission (36.1 +/- 2.1 weeks vs 37.2 +/- 1.9 weeks; P < .005), lower gestational age at delivery (36.5 +/- 1.9 weeks vs 37.7 +/- 1.7 weeks; P < .005), lower birthweight (2429 +/- 590 g vs 3013 +/- 597 g; P < .0001), and a higher admission rate to neonatal intensive care unit (17/51 vs 6/48; odds ratio, 3.5; 95% confidence interval, 1.2-9.5). No significant difference in the occurrence of maternal complications (10/51 vs 6/48; odds ratio, 1.7; 95% confidence interval, 0.5-4.9) was registered.

Conclusion: Women with late-onset preeclampsia show a higher risk of perinatal complications if uterine resistance is increased although maternal outcome does not seem to be related to Doppler findings.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Anthracenes
  • Arteries / diagnostic imaging
  • Female
  • Humans
  • Pre-Eclampsia / diagnostic imaging*
  • Pre-Eclampsia / physiopathology
  • Pregnancy
  • Pregnancy Outcome*
  • Pregnancy Trimester, Third
  • Prognosis
  • Regional Blood Flow
  • Ultrasonography, Doppler*
  • Ultrasonography, Prenatal*
  • Uterus / blood supply*

Substances

  • Anthracenes
  • gasteriacenone A