Efficacy and safety of darunavir and etravirine in an antiretroviral multi-experienced youth with vertically HIV-1 infection

Raffaella Rosso; C Bernardini; B Bruzzone; G Secondo; G Icardi; C Viscoli; A Di Biagio

doi:10.1186/2047-783x-14-3-136

Efficacy and safety of darunavir and etravirine in an antiretroviral multi-experienced youth with vertically HIV-1 infection

Eur J Med Res. 2009 Mar 17;14(3):136-8. doi: 10.1186/2047-783x-14-3-136.

Authors

Raffaella Rosso¹, C Bernardini, B Bruzzone, G Secondo, G Icardi, C Viscoli, A Di Biagio

Affiliation

¹ Department of Infectious Diseases, University of Genoa, San Martino Hospital, Genova, Italy. [email protected]

Abstract

Multiclass-drug resistance, often caused by poor treatment compliance, is a challenging problem in all categories of HIV-infected patients. Selective pressure is higher in youth for both biological and behavioral reasons. We report the case of a 15-year-old Caucasian male, with vertically acquired HIV-1 infection, who failed several lines of antiretroviral therapy and was successfully treated with darunavir/ritonavir and etravirine.

Publication types

Case Reports

MeSH terms

Adolescent
Darunavir
Drug Resistance, Multiple, Viral / drug effects
Drug Therapy, Combination
HIV Infections / drug therapy*
HIV Infections / transmission*
HIV Protease Inhibitors / therapeutic use*
Humans
Infectious Disease Transmission, Vertical*
Male
Nitriles
Pyridazines / therapeutic use*
Pyrimidines
Ritonavir / therapeutic use
Sulfonamides / therapeutic use*
Treatment Outcome

Substances

HIV Protease Inhibitors
Nitriles
Pyridazines
Pyrimidines
Sulfonamides
etravirine
Ritonavir
Darunavir