Functional brain-electrical correlates of negative priming in the flanker task: evidence for episodic retrieval

Psychophysiology. 2009 Jul;46(4):807-17. doi: 10.1111/j.1469-8986.2009.00819.x. Epub 2009 Apr 6.

Abstract

Negative priming (NP) refers to inefficient responding when previous distractors become targets. NP may reflect persisting inhibition of former distractors and/or retrieval of task-inappropriate information from the primes. In an event-related potential (ERP) study of the flanker task, NP was accompanied by reduced positivity in the P300 time range. The early portion of this effect was shared with a target-repetition condition and hence may indicate retrieval processes cued by repeated stimuli. A subsequent N400-like component was specific for NP and may reflect processing of the retrieved task-inappropriate information. In addition, NP effects on the lateralized readiness potential (LRP) matched predictions of the episodic-retrieval view. NP effects on P300, N400, and response-locked LRP were stronger in participants with above-median behavioral NP, confirming the significance of these ERP effects for NP. Overall, findings support episodic-retrieval explanations of NP.

MeSH terms

  • Adult
  • Attention / physiology*
  • Cues*
  • Electroencephalography
  • Event-Related Potentials, P300 / physiology
  • Female
  • Functional Laterality / physiology
  • Humans
  • Male
  • Photic Stimulation
  • Psychomotor Performance / physiology*
  • Young Adult