Abstract
We report a case of Macrophomina phaseolina skin infection in an immunocompromised child with acute myeloid leukemia, which was treated successfully with posaconazole without recurrence after a hematopoietic stem cell transplant. The fungus was identified by DNA sequencing using both the internal transcribed spacer and D1/D2 region of the 28S ribosomal DNA gene.
Publication types
-
Case Reports
-
Research Support, N.I.H., Extramural
-
Research Support, Non-U.S. Gov't
-
Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
-
Antifungal Agents / therapeutic use
-
Ascomycota / isolation & purification*
-
Child
-
DNA, Fungal / chemistry
-
DNA, Fungal / genetics
-
DNA, Ribosomal Spacer / chemistry
-
DNA, Ribosomal Spacer / genetics
-
Dermatomycoses / diagnosis*
-
Dermatomycoses / drug therapy
-
Dermatomycoses / microbiology
-
Female
-
Humans
-
Immunocompromised Host
-
Leukemia, Myeloid, Acute / complications*
-
Molecular Sequence Data
-
Sequence Analysis, DNA
-
Skin / pathology
-
Triazoles / therapeutic use
Substances
-
Antifungal Agents
-
DNA, Fungal
-
DNA, Ribosomal Spacer
-
Triazoles
-
posaconazole
Associated data
-
GENBANK/FJ415067
-
GENBANK/FJ415068