Outbreak of nontuberculous mycobacterial subcutaneous infections related to multiple mesotherapy injections

Anne Carbonne; Florence Brossier; Isabelle Arnaud; Iheb Bougmiza; Eric Caumes; Jean-Paul Meningaud; Sylvie Dubrou; Vincent Jarlier; Emmanuelle Cambau; Pascal Astagneau

doi:10.1128/JCM.00196-09

Outbreak of nontuberculous mycobacterial subcutaneous infections related to multiple mesotherapy injections

J Clin Microbiol. 2009 Jun;47(6):1961-4. doi: 10.1128/JCM.00196-09. Epub 2009 Apr 22.

Authors

Anne Carbonne¹, Florence Brossier, Isabelle Arnaud, Iheb Bougmiza, Eric Caumes, Jean-Paul Meningaud, Sylvie Dubrou, Vincent Jarlier, Emmanuelle Cambau, Pascal Astagneau

Affiliation

¹ C-CLIN Nord, Institut des Cordeliers, 15 rue de l'Ecole de Médecine, 75006 Paris, France. [email protected]

Abstract

We describe an outbreak of severe subcutaneous infections due to nontuberculous mycobacteria following mesotherapy. Epidemiological studies and molecular comparisons of Mycobacterium chelonae strains from different patients and the environment suggested that contamination may be associated with inappropriate cleaning of the multiple-injection device with tap water.

Publication types

Case Reports

MeSH terms

Adult
Bacterial Typing Techniques
Cluster Analysis
DNA Fingerprinting
Disease Outbreaks*
Electrophoresis, Gel, Pulsed-Field
Environmental Microbiology
Female
Humans
Injections / adverse effects*
Male
Middle Aged
Molecular Epidemiology
Mycobacterium Infections / diagnosis*
Mycobacterium Infections / epidemiology*
Mycobacterium Infections / microbiology
Mycobacterium chelonae / classification
Mycobacterium chelonae / genetics
Mycobacterium chelonae / isolation & purification*
Skin Diseases, Bacterial / diagnosis*
Skin Diseases, Bacterial / epidemiology*
Skin Diseases, Bacterial / microbiology
Young Adult