Surgical resection is the main and most effective treatment for gastrointestinal stromal tumours (GISTs) and for all benign gastric tumours. All such tumours should be approached with the intention of performing complete en bloc removal of the tumour, achieving microscopically tumour-free pathological resection margins. More extensive surgery fails to guarantee better results over time. Consequently, wedge resection of the stomach ensures adequate therapy. Our personal experience with laparoscopic wedge resection for a gastrointestinal stromal tumour is described, demonstrating equivalent efficacy, greater safety, and applicability, and better postoperative results with this surgical approach.