Standardization of the first-trimester fetal cardiac examination using spatiotemporal image correlation with tomographic ultrasound and color Doppler imaging

Ultrasound Obstet Gynecol. 2009 Jun;33(6):652-6. doi: 10.1002/uog.6372.

Abstract

Objective: The challenges of the first-trimester examination of the fetal heart may in part be overcome by technical advances in three-dimensional (3D) ultrasound techniques. Our aim was to standardize the first-trimester 3D imaging approach to the cardiac examination to provide the most consistent and accurate display of anatomy.

Methods: Low-risk women with normal findings on first-trimester screening at 11 to 13 + 6 weeks had cardiac ultrasound using the following sequence: (1) identification of the four-chamber view; (2) four-dimensional (4D) volume acquisition with spatiotemporal image correlation (STIC) and color Doppler imaging (angle = 20 degrees, sweep 10 s); (3) offline, tomographic ultrasound imaging (TUI) analysis with standardized starting plane (four-chamber view), slice number and thickness; (4) assessment of fetal cardiac anatomy (four-chamber view, cardiac axis, size and symmetry, atrioventricular valves, great arteries and descending aorta) with and without color Doppler.

Results: 107 consecutive women (age, 16-42 years, body mass index 17.2-50.2 kg/m(2)) were studied. A minimum of three 3D volumes were obtained for each patient, transabdominally in 91.6%. Fetal motion artifact required acquisition of more than three volumes in 20%. The median time for TUI offline analysis was 100 (range, 60-240) s. Individual anatomic landmarks were identified in 89.7-99.1%. Visualization of all structures in one panel was observed in 91 patients (85%).

Conclusion: Starting from a simple two-dimensional cardiac landmark-the four-chamber view-the standardized STIC-TUI technique enables detailed segmental cardiac evaluation of the normal fetal heart in the first trimester.

Publication types

  • Validation Study

MeSH terms

  • Adolescent
  • Adult
  • Cardiac Volume / physiology*
  • Echocardiography, Doppler, Color / methods
  • Echocardiography, Doppler, Color / standards*
  • Echocardiography, Four-Dimensional / methods
  • Echocardiography, Four-Dimensional / standards
  • Echocardiography, Three-Dimensional / methods
  • Echocardiography, Three-Dimensional / standards
  • Female
  • Fetal Heart / diagnostic imaging*
  • Gestational Age
  • Humans
  • Pregnancy
  • Pregnancy Trimester, First
  • Prospective Studies
  • Ultrasonography, Prenatal / methods
  • Ultrasonography, Prenatal / standards*
  • Young Adult