We report the case of an 8-year-old boy who developed a distinctive skin eruption after oral treatment with risperidone for the syndrome of attention deficiency with hyperactivity. The clinical findings were compatible with so-called symmetrical drug related intertriginous and flexural exanthema, also known as Baboon syndrome. Although epicutaneous patch testing with the offending drug was negative, drug rechallenge produced a recurrence of the skin findings. To the best of our knowledge, this is the first case of symmetrical drug related intertriginous and flexural exanthema reported due to risperidone.