Abstract
A 56-year-old man with chronic hepatitis C (HCV) was treated with interferon therapy and achieved sustained virological response (SVR) in 1993. Thirteen years later, in 2006 two liver tumors, 35-mm and 11-mm in diameter respectively, were detected in liver segment 6. Hepatic resection was performed, and pathologically one nodule was diagnosed as cholangiocellular carcinoma (CCC) and the other hepatocellular carcinoma (HCC). Continuity was not recognized between these tumors, thus, we diagnosed this case as double cancer (CCC and HCC). Here, we report a rare case of double cancer (CCC and HCC) that developed 13 years after achieving SVR for HCV infection.
Publication types
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Case Reports
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English Abstract
MeSH terms
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Biomarkers / blood
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Carcinoma, Hepatocellular* / diagnosis
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Carcinoma, Hepatocellular* / pathology
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Carcinoma, Hepatocellular* / surgery
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Cholangiocarcinoma* / diagnosis
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Cholangiocarcinoma* / pathology
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Cholangiocarcinoma* / surgery
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Hepacivirus / genetics
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Hepatitis C, Chronic / complications*
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Hepatitis C, Chronic / diagnosis
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Hepatitis C, Chronic / drug therapy*
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Hepatitis C, Chronic / virology
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Humans
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Interferon-alpha / administration & dosage*
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Liver Neoplasms* / diagnosis
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Liver Neoplasms* / pathology
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Liver Neoplasms* / surgery
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Male
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Middle Aged
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Neoplasms, Multiple Primary*
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RNA, Viral / blood
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Time Factors
Substances
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Biomarkers
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Interferon-alpha
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RNA, Viral