Correction for chemical-shift artifacts in 19F imaging of PFOB: simultaneous multislice imaging

Magn Reson Med. 1991 Sep;21(1):21-9. doi: 10.1002/mrm.1910210105.

Abstract

One of the difficulties encountered in 19F NMR imaging of fluorinated blood substitutes is that these compounds often exhibit complex multipeak spectra. These peaks result in chemical-shift artifacts along the readout direction and blurred images. In addition, each peak excites a different slice (mis-selection) when a slice selection gradient is applied during the selective rf pulse. A simultaneous multislice imaging method has been developed to solve the inherent problem of mis-selection. The essence of this method is to use the two strongest peaks of the spectrum to excite controlled different multiple slices simultaneously, with or without a slice gap. The images corresponding to the two spectral lines are then separated from in- and out-of-phase images (Dixon method). This method corrects the problem of mis-selection and either improves the SNR or increases the number of slices over spectrally selective methods which image only one peak.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Artifacts*
  • Blood Substitutes*
  • Contrast Media
  • Fluorine
  • Fluorocarbons*
  • Humans
  • Hydrocarbons, Brominated
  • Magnetic Resonance Imaging / methods*

Substances

  • Blood Substitutes
  • Contrast Media
  • Fluorocarbons
  • Hydrocarbons, Brominated
  • Fluorine
  • perflubron