Abstract
A new alkaloid, daphenylline (1), with an unprecedented rearranged 22-nor-calyciphylline skeleton, was isolated from the fruits of Daphniphyllum longeracemosum. Its structure and stereochemistry were elucidated on the basis of spectroscopic and computational approaches. A plausible biosynthetic pathway of 1 was also proposed.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alkaloids / chemistry*
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Alkaloids / isolation & purification*
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Alkaloids / pharmacology
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Drug Screening Assays, Antitumor
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Drugs, Chinese Herbal / chemistry*
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Drugs, Chinese Herbal / isolation & purification*
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Drugs, Chinese Herbal / pharmacology
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Humans
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Molecular Structure
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Saxifragaceae / chemistry*
Substances
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Alkaloids
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Drugs, Chinese Herbal
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daphenylline