Comparison of the BD Phoenix system with the cefoxitin disk diffusion test for detection of methicillin resistance in Staphylococcus aureus and coagulase-negative staphylococci

Antonella Mencacci; Ines Montecarlo; Francesca Gonfia; Amedeo Moretti; Angela Cardaccia; Senia Farinelli; Maria Rita Pagliochini; Angela Giuliani; Michela Basileo; Maria Bruna Pasticci; Francesco Bistoni

doi:10.1128/JCM.02431-08

Comparison of the BD Phoenix system with the cefoxitin disk diffusion test for detection of methicillin resistance in Staphylococcus aureus and coagulase-negative staphylococci

J Clin Microbiol. 2009 Jul;47(7):2288-91. doi: 10.1128/JCM.02431-08. Epub 2009 May 13.

Authors

Antonella Mencacci¹, Ines Montecarlo, Francesca Gonfia, Amedeo Moretti, Angela Cardaccia, Senia Farinelli, Maria Rita Pagliochini, Angela Giuliani, Michela Basileo, Maria Bruna Pasticci, Francesco Bistoni

Affiliation

¹ Department of Experimental Medicine and Biochemical Sciences, University of Perugia, Perugia, Italy. [email protected]

Abstract

The BD Phoenix system was compared to the cefoxitin disk diffusion test for detection of methicillin (meticillin) resistance in 1,066 Staphylococcus aureus and 1,121 coagulase-negative staphylococcus (CoNS) clinical isolates. The sensitivity for Phoenix was 100%. The specificities were 99.86% for S. aureus and 88.4% for CoNS.

Publication types

Comparative Study
Evaluation Study

MeSH terms

Anti-Bacterial Agents / pharmacology*
Cefoxitin / pharmacology*
Coagulase / biosynthesis
Humans
Methicillin Resistance*
Microbial Sensitivity Tests / methods
Sensitivity and Specificity
Staphylococcus / drug effects*

Substances

Anti-Bacterial Agents
Coagulase
Cefoxitin