We study a two-class classification problem with a large number of features, out of which many are useless and only a few are useful, but we do not know which ones they are. The number of features is large compared with the number of training observations. Calibrating the model with 4 key parameters--the number of features, the size of the training sample, the fraction, and strength of useful features--we identify a region in parameter space where no trained classifier can reliably separate the two classes on fresh data. The complement of this region--where successful classification is possible--is also briefly discussed.