Propionibacterium skull osteomyelitis treated with daptomycin

Clin Neurol Neurosurg. 2009 Sep;111(7):610-2. doi: 10.1016/j.clineuro.2009.04.003. Epub 2009 May 17.

Abstract

Propionibacterium acnes (P. acnes) is emerging as a pathogen in postneurosurgical infections. A case of cranial bone flap infection due to P. acnes successfully treated with daptomycin is presented. This case demonstrates the potential of daptomycin as an option in the treatment of P. acnes.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / therapeutic use*
  • Ciprofloxacin / therapeutic use
  • Daptomycin / therapeutic use*
  • Gram-Positive Bacterial Infections / drug therapy*
  • Gram-Positive Bacterial Infections / microbiology
  • Gram-Positive Bacterial Infections / pathology
  • Humans
  • Male
  • Meningioma / complications
  • Meningioma / pathology
  • Meningioma / surgery
  • Neurosurgical Procedures
  • Osteomyelitis / drug therapy*
  • Osteomyelitis / microbiology
  • Osteomyelitis / pathology
  • Propionibacterium acnes*
  • Skull / pathology*
  • Sphenoid Sinus / pathology
  • Sphenoid Sinus / surgery
  • Surgical Flaps
  • Surgical Wound Infection / diagnosis*
  • Surgical Wound Infection / microbiology
  • Young Adult

Substances

  • Anti-Bacterial Agents
  • Ciprofloxacin
  • Daptomycin