Abstract
Partial atlE sequencing (atlE nucleotides 2782 to 3114 [atlE(2782-3114)]) was performed in 41 Staphylococcus epidermidis isolates from prosthetic joint infections (PJIs) and 44 isolates from skin as controls. The atlE(2782-3114) allele 1 (type strain sequence) was significantly more frequent in PJI strains (38/41 versus 29/44 in controls; P = 0.0023). Most PJI strains were positive for mecA, icaA/icaD, and IS256, and most belonged to the sequence type 27 subgroup, suggesting the involvement of few related clones.
MeSH terms
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Alleles
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Bacterial Proteins / genetics*
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Bacterial Typing Techniques
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Cluster Analysis
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DNA, Bacterial / chemistry
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DNA, Bacterial / genetics
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Genotype
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Humans
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Joint Diseases / microbiology*
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Molecular Sequence Data
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Prosthesis-Related Infections / microbiology*
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Sequence Analysis, DNA
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Staphylococcal Infections / microbiology*
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Staphylococcus epidermidis / classification*
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Staphylococcus epidermidis / genetics*
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Staphylococcus epidermidis / isolation & purification
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Virulence Factors / genetics
Substances
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Bacterial Proteins
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DNA, Bacterial
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Virulence Factors
Associated data
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GENBANK/FJ009419
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GENBANK/FJ009420
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GENBANK/FJ009421
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GENBANK/FJ009422
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GENBANK/FJ009423
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GENBANK/FJ009424
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GENBANK/FJ009425
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GENBANK/FJ009426
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GENBANK/FJ009427
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GENBANK/FJ009428