Abstract
Exopolysaccharides have prebiotic potential and contribute to the rheology and texture of fermented foods. Here we have analyzed the in vitro bioavailability and immunomodulatory properties of the 2-substituted (1,3)-beta-D-glucan-producing bacterium Pediococcus parvulus 2.6. It resists gastrointestinal stress, adheres to Caco-2 cells, and induces the production of inflammation-related cytokines by polarized macrophages.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Bacterial Adhesion
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Caco-2 Cells
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Cytokines / metabolism
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Humans
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Immunologic Factors / pharmacology*
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Macrophages / immunology
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Macrophages / microbiology
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Pediococcus / immunology*
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Pediococcus / metabolism*
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Pediococcus / physiology
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Probiotics / pharmacology*
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Proteoglycans
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beta-Glucans / metabolism*
Substances
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Cytokines
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Immunologic Factors
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Proteoglycans
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beta-Glucans
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polysaccharide-K