Management of biliary complications following living donor liver transplantation--a single center experience

Langenbecks Arch Surg. 2009 Nov;394(6):1025-31. doi: 10.1007/s00423-009-0506-8. Epub 2009 May 27.

Abstract

Purpose: Biliary complications (BC) after living donor liver transplantation (LDLT) are reported in up to 32%. We retrospectively reviewed the biliary reconstruction after 95 LDLT.

Methods: Eighty-one right hemiliver grafts and 14 left lateral section grafts were transplanted. Bile duct anastomoses were performed as duct-to-duct (DD) or bilioenteric anastomosis (RYHJ); multiple bile ducts were anastomosed using a ductoplasty or multiple direct bile duct anastomoses.

Results: After right hemiliver LDLT, a total of 45.5% of BC was observed, with an incidence of 27.7% in case of DD anastomosis and 18.8% in case of RYHJ. After DD anastomosis, strictures were successfully treated endoscopically in 50%; insufficiencies mainly required reoperations.

Conclusion: BC still account for a high percentage of morbidity and mortality after LDLT. DD anastomoses are performed more frequently and are feasible in cases with simple biliary anatomy; RYHJ is the gold standard for the reconstruction of multiple bile ducts.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Bile Duct Diseases / diagnosis
  • Bile Duct Diseases / etiology*
  • Bile Duct Diseases / surgery*
  • Child
  • Child, Preschool
  • Choledochostomy
  • Cohort Studies
  • Humans
  • Infant
  • Jejunostomy
  • Liver Transplantation / adverse effects*
  • Living Donors*
  • Middle Aged
  • Portoenterostomy, Hepatic
  • Retrospective Studies
  • Treatment Outcome
  • Young Adult