Chemically inducible inactivation of protein synthesis in genetically targeted neurons

J Neurosci. 2009 May 27;29(21):6761-6. doi: 10.1523/JNEUROSCI.1280-09.2009.
No abstract available

Publication types

  • Research Support, N.I.H., Intramural

MeSH terms

  • Analysis of Variance
  • Animals
  • Brain-Derived Neurotrophic Factor / pharmacology
  • Cells, Cultured
  • Dendritic Spines / drug effects
  • Dendritic Spines / metabolism
  • Electric Stimulation / methods
  • Excitatory Postsynaptic Potentials / drug effects
  • Excitatory Postsynaptic Potentials / physiology
  • Green Fluorescent Proteins / genetics
  • Hippocampus / cytology
  • Humans
  • In Vitro Techniques
  • Long-Term Potentiation / drug effects
  • Long-Term Potentiation / physiology
  • Mice
  • Mutation / genetics
  • Neurons / cytology
  • Neurons / drug effects
  • Neurons / metabolism*
  • Patch-Clamp Techniques / methods
  • Protein Biosynthesis / drug effects
  • Protein Biosynthesis / physiology*
  • Rats
  • Tacrolimus / analogs & derivatives
  • Tacrolimus / pharmacology
  • Tacrolimus Binding Protein 1A / genetics
  • Tacrolimus Binding Proteins / genetics
  • Tacrolimus Binding Proteins / metabolism
  • Time Factors
  • Transfection / methods
  • eIF-2 Kinase / genetics
  • eIF-2 Kinase / metabolism*

Substances

  • AP20187
  • Brain-Derived Neurotrophic Factor
  • enhanced green fluorescent protein
  • Green Fluorescent Proteins
  • eIF-2 Kinase
  • Tacrolimus Binding Protein 1A
  • Tacrolimus Binding Proteins
  • Tacrolimus