Selective engraftment of donor CD4+25high FOXP3-positive T cells in IPEX syndrome after nonmyeloablative hematopoietic stem cell transplantation

Blood. 2009 May 28;113(22):5689-91. doi: 10.1182/blood-2009-02-206359.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Abnormalities, Multiple / immunology
  • Abnormalities, Multiple / therapy
  • Blood Donors
  • CD4-Positive T-Lymphocytes / immunology
  • CD4-Positive T-Lymphocytes / metabolism
  • CD4-Positive T-Lymphocytes / transplantation*
  • Cell Separation / methods
  • Forkhead Transcription Factors / metabolism*
  • Graft Survival / immunology
  • Hematopoietic Stem Cell Transplantation*
  • Humans
  • Infant
  • Interleukin-2 Receptor alpha Subunit / metabolism*
  • Lymphoproliferative Disorders / complications
  • Lymphoproliferative Disorders / therapy*
  • Male
  • Polyendocrinopathies, Autoimmune / complications
  • Polyendocrinopathies, Autoimmune / therapy
  • Syndrome

Substances

  • FOXP3 protein, human
  • Forkhead Transcription Factors
  • Interleukin-2 Receptor alpha Subunit