Developmental biology: The early heart remodelled

Nature. 2009 Jun 4;459(7247):654-5. doi: 10.1038/459654a.

Abstract

What factors direct the formation of heart muscle in the developing embryo? Unexpectedly, a chromatin-remodelling protein complex turns out to be a crucial determinant of cardiac-cell fate.

Publication types

  • Comment
  • News

MeSH terms

  • Animals
  • Cell Differentiation
  • Chromatin Assembly and Disassembly / physiology
  • Chromosomal Proteins, Non-Histone / genetics
  • Chromosomal Proteins, Non-Histone / metabolism*
  • Gene Expression Regulation, Developmental*
  • Heart / embryology*
  • Mice
  • Multiprotein Complexes / metabolism
  • Myocytes, Cardiac / cytology
  • Myocytes, Cardiac / metabolism

Substances

  • Chromosomal Proteins, Non-Histone
  • Multiprotein Complexes