Identification of a novel allele HLA-A*2489 by sequence-based typing in a Chinese individual

Y Xiao; X-Y Zhou; N Liu; Z-X Zhang; J-P Cai

doi:10.1111/j.1399-0039.2009.01290.x

Identification of a novel allele HLA-A*2489 by sequence-based typing in a Chinese individual

Tissue Antigens. 2009 Sep;74(3):249-50. doi: 10.1111/j.1399-0039.2009.01290.x. Epub 2009 Jun 2.

Authors

Y Xiao¹, X-Y Zhou, N Liu, Z-X Zhang, J-P Cai

Affiliation

¹ The Key Laboratory of Geriatrics, Beijing Institute of Geriatrics, Beijing Hospital, Ministry of Health, Beijing, China.

PMID: 19497034
DOI: 10.1111/j.1399-0039.2009.01290.x

Abstract

A novel human leukocyte antigen-A allele, A*2489, was identified in a Chinese registered donor. The A*2489 allele differs from the closest matching allele A*2428 by two nucleotide substitutions, 257(A-->G) and 265(G-->C), in exon 2.

MeSH terms

Alleles*
Amino Acid Sequence
Amino Acid Substitution
Arginine / metabolism
Asian People / genetics*
Base Sequence
Bone Marrow Cells / cytology
China
Codon
DNA Primers / genetics
Exons
Gene Frequency
Genotype
Glycine / metabolism
HLA-A Antigens / chemistry
HLA-A Antigens / genetics*
Histocompatibility Testing / methods*
Humans
Microspheres
Molecular Sequence Data
Oligonucleotides / genetics
Protein Structure, Tertiary / genetics
Sequence Analysis, DNA / methods
Sequence Homology, Nucleic Acid
Terminology as Topic
Tissue Donors

Substances

Codon
DNA Primers
HLA-A Antigens
Oligonucleotides
Arginine
Glycine