Aspergillus infection limited to the anastomosed artery following renal transplantation: a report of 4 cases

Transpl Infect Dis. 2009 Aug;11(4):363-6. doi: 10.1111/j.1399-3062.2009.00402.x. Epub 2009 May 21.

Abstract

We present 4 cases of Aspergillus fumigatus infection limited to the anastomosed artery following renal transplantation. All grafts were nephrectomized. Two patients received 2 weeks of itraconazole therapy; both showing recurrence of pseudoaneurysms following discontinuation of therapy. Another 2 patients received 3 months of itraconazole therapy without recurrence of pseudoaneurysms. Surgical interventions were life saving. Resection of infected tissues and 3 months of antifungal therapy seemed to give better results than shorter antifungal strategies.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anastomosis, Surgical
  • Aneurysm, False / diagnosis
  • Aneurysm, False / etiology
  • Aneurysm, False / surgery
  • Antifungal Agents / therapeutic use
  • Aspergillosis / drug therapy
  • Aspergillosis / microbiology*
  • Aspergillus fumigatus / isolation & purification*
  • Female
  • Humans
  • Itraconazole / therapeutic use
  • Kidney Transplantation / adverse effects*
  • Male
  • Renal Artery / injuries
  • Renal Artery / microbiology*

Substances

  • Antifungal Agents
  • Itraconazole