Three new HLA-A alleles determined by sequence-based typing: A*2493, A*2918 and A*0342

Tissue Antigens. 2009 Sep;74(3):250-1. doi: 10.1111/j.1399-0039.2009.01289.x. Epub 2009 Jun 4.

Abstract

In this study, we report the identification of three new human leukocyte antigen class I alleles: A*2493, A*2918 and A*0342 found by routine typing using commercial kits. The names A*2493 (HWS 10005702), A*2918 (HWS 10005703) and A*0342 (HWS 10005705) have been officially assigned by the World Health Organization Nomenclature Committee in August 2008.

MeSH terms

  • Adult
  • Alleles*
  • Amino Acid Sequence
  • Amino Acid Substitution
  • Arginine / metabolism
  • Base Sequence
  • Black People / ethnology
  • Black People / genetics
  • Bone Marrow Cells / cytology
  • Codon
  • DNA Primers / genetics
  • Exons / genetics
  • Female
  • Glutamine / metabolism
  • HLA Antigens / genetics*
  • Histocompatibility Testing / methods*
  • Humans
  • Male
  • Molecular Sequence Data
  • Oligonucleotide Probes / genetics
  • Polymerase Chain Reaction
  • Reagent Kits, Diagnostic
  • Sequence Analysis, DNA / methods
  • Tissue Donors
  • Valine / metabolism
  • White People / genetics

Substances

  • Codon
  • DNA Primers
  • HLA Antigens
  • Oligonucleotide Probes
  • Reagent Kits, Diagnostic
  • Glutamine
  • Arginine
  • Valine