Efficacy of cyclosporine A treatment in relapsing febrile lobular panniculitis associated with small vessel vasculitis

Rheumatol Int. 2010 Apr;30(6):797-9. doi: 10.1007/s00296-009-0990-8. Epub 2009 Jun 9.

Abstract

Weber-Christian Disease (WCD), also known as relapsing febrile lobular non-suppurative panniculitis, is a rare condition characterized by recurrent subcutaneous inflammatory nodules in the adipose tissue in addition to fever, malaise and other systemic manifestations such as polyarthralgia and polymyalgia. The association with small vessel vasculitis has been rarely reported. We report here an unusual case of WCD associated with small vessels vasculitis also describing the efficacy of Cyclosporin A treatment.

Publication types

  • Case Reports

MeSH terms

  • Biopsy
  • Blood Vessels / drug effects
  • Blood Vessels / immunology
  • Blood Vessels / pathology
  • Child
  • Chronic Disease
  • Cyclosporine / pharmacology*
  • Cyclosporine / therapeutic use
  • Humans
  • Immunosuppressive Agents / pharmacology
  • Immunosuppressive Agents / therapeutic use
  • Male
  • Panniculitis, Nodular Nonsuppurative / complications*
  • Panniculitis, Nodular Nonsuppurative / drug therapy*
  • Panniculitis, Nodular Nonsuppurative / physiopathology
  • Recurrence
  • Skin / drug effects
  • Skin / immunology
  • Skin / pathology
  • Treatment Outcome
  • Vasculitis / drug therapy*
  • Vasculitis / etiology*
  • Vasculitis / physiopathology

Substances

  • Immunosuppressive Agents
  • Cyclosporine