Molecular markers of chloroquine resistance in Plasmodium falciparum in Sri Lanka: frequency before revision of the antimalarial drug policy

Ann Trop Med Parasitol. 2009 Jun;103(4):351-6. doi: 10.1179/136485909X435067.

Authors

H C Hapuarachchi¹, S Abeysundara, M Y D Dayanath, A Manamperi, W Abeyewickreme, N R de Silva

Affiliation

¹ Department of Parasitology, Faculty of Medicine, University of Kelaniya, P.O. Box 6, Thalagolla Road, Ragama, Sri Lanka.

PMID: 19508753
DOI: 10.1179/136485909X435067

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Antimalarials / therapeutic use*
Biomarkers / analysis
Chloroquine / therapeutic use*
Drug Monitoring
Drug Resistance / genetics
Humans
Malaria, Falciparum / drug therapy*
Malaria, Falciparum / epidemiology
Membrane Transport Proteins / genetics*
Military Personnel
Multidrug Resistance-Associated Proteins / genetics*
Mutation / genetics
Plasmodium falciparum* / drug effects
Plasmodium falciparum* / genetics
Prevalence
Protozoan Proteins / genetics*
Sri Lanka / epidemiology
Statistics as Topic
Time Factors

Substances

Antimalarials
Biomarkers
Mdr1 protein, Plasmodium falciparum
Membrane Transport Proteins
Multidrug Resistance-Associated Proteins
PfCRT protein, Plasmodium falciparum
Protozoan Proteins
Chloroquine