Background: Radical vaginectomy (RV) is related to significant bladder dysfunctions. We describe 2 cases of RV with nerve-sparing technique (NSRV).
Case reports: A 58-year-old woman with a diagnosis of locally advanced cervical cancer underwent neoadjuvant chemotherapy with local and nodal progression of disease. The patient underwent NS radical hysterectomy plus NSRV, with prompt recovery of bladder function. A 14-year-old adolescent girl with a diagnosis of recurrent embryonal-botryoidal rhabdomyosarcoma was referred to us. She underwent 6 courses of chemotherapy with persistent disease. She then underwent NSRV. Two months after the surgical procedure, she was able to void the bladder.
Conclusions: These are the first 2 cases of NSRV reported in literature. This new surgical technique is feasible, with prompt recovery of bladder function.