Abstract
The DNA repair machinery has been co-opted for antigenic variation in African trypanosomes. New work directly demonstrates that a double-strand break initiates a switch in the expressed variant surface coat.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Africa
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Animals
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Antigenic Variation / genetics*
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DNA Breaks*
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DNA Breaks, Double-Stranded
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Trypanosoma / genetics*
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Variant Surface Glycoproteins, Trypanosoma / genetics
Substances
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Variant Surface Glycoproteins, Trypanosoma