[Exposure to environmental tobacco smoke and salivary cotinine concentration in a sample of students from Barcelona, Spain]

Med Clin (Barc). 2009 Oct 31;133(16):622-5. doi: 10.1016/j.medcli.2009.03.022. Epub 2009 Jun 10.
[Article in Spanish]

Abstract

Background and objective: The objective of this study was to assess the exposure to environmental tobacco smoke (ETS) by means of the concentration of salivary cotinine in a sample of adolescent students, and its relationship with active and passive tobacco consumption.

Methods: A cross-sectional survey was conducted in 92 secondary education and high school pupils (16-20 years). Salivary samples were collected and salivary cotinine was measured by gas chromatography/mass spectrometry. Salivary cotinine medians and interquartile ranges were calculated. Significant statistical differences were detected with the non parametric test for medians.

Results: The median of salivary cotinine concentration in current smokers was 91.5 ng/ml (RI: 62.4-125); in former smokers 7.9 ng/ml (RI: 5.1-15.5) and in never smokers 1.9 ng/ml (RI: 0-3.6). In smokers of more than 10 cigarettes per day, the result was 98.3 ng/ml (RI:63.4-142.9). Among non-smokers (never-smoker and ex-smokers), the median of salivary cotinine in non-smokers living with smokers was 3.3 ng/ml (RI: 0-8.6) versus 2.9 ng/ml (RI: 1.1-6.9) in those living with non-smokers.

Conclusions: The salivary cotinine concentration increases with the intensity of tobacco consumption and the perception of passive exposure to tobacco smoke.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Cotinine / analysis*
  • Cross-Sectional Studies
  • Environmental Exposure / analysis*
  • Female
  • Humans
  • Male
  • Saliva / chemistry*
  • Spain
  • Students
  • Tobacco Smoke Pollution / analysis*
  • Urban Health
  • Young Adult

Substances

  • Tobacco Smoke Pollution
  • Cotinine