The proteasome's crown for destruction

Mol Cell. 2009 Jun 12;34(5):519-20. doi: 10.1016/j.molcel.2009.05.021.

Abstract

Three recent Molecular Cell papers from Zhang et al. (2009a, 2009b) and Djuranovic et al. (2009) provide new insights into how proteasomal ATPases recognize, unfold, and translocate their substrates, thus enhancing our understanding of regulated proteolysis.

Publication types

  • Comment

MeSH terms

  • Adenosine Triphosphatases / metabolism
  • Adenosine Triphosphatases / physiology
  • Models, Molecular*
  • Proteasome Endopeptidase Complex / chemistry
  • Proteasome Endopeptidase Complex / physiology*
  • Protein Folding
  • Proteins / metabolism

Substances

  • Proteins
  • Proteasome Endopeptidase Complex
  • Adenosine Triphosphatases