A highly enantioselective allylic amination reaction using a commercially available chiral rhodium catalyst: resolution of racemic allylic carbonates

Org Lett. 2009 Jul 16;11(14):3140-2. doi: 10.1021/ol901031b.

Abstract

A novel method for the kinetic resolution of unsymmetrical acyclic allylic carbonates and the concurrent synthesis of enantioenriched secondary amines using a commercially available chiral catalyst is disclosed.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Allyl Compounds / chemistry*
  • Amines / chemical synthesis*
  • Amines / chemistry
  • Carbonates / chemistry*
  • Catalysis
  • Molecular Structure
  • Rhodium / chemistry*
  • Stereoisomerism

Substances

  • Allyl Compounds
  • Amines
  • Carbonates
  • Rhodium