Super-helices self-assembled from a binary system of amphiphilic polypeptide block copolymers and polypeptide homopolymers

Chem Commun (Camb). 2009 May 21:(19):2709-11. doi: 10.1039/b823367e. Epub 2009 Mar 27.

Abstract

We report here a discovery that amphiphilic polypeptide block copolymers and polypeptide homopolymers are able to aggregate together into super-helical structures of rods and rings, in which polypeptide chains form the core and PEG chains form the shell.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Microscopy, Electron, Transmission
  • Molecular Weight
  • Peptides / chemistry*
  • Polyethylene Glycols / chemistry*
  • Polyglutamic Acid / analogs & derivatives
  • Polyglutamic Acid / chemistry
  • Polymers / chemistry
  • Protein Structure, Secondary

Substances

  • Peptides
  • Polymers
  • poly-gamma-benzyl-L-glutamate
  • Polyglutamic Acid
  • Polyethylene Glycols