Disordered-eating attitudes in relation to bone mineral density and markers of bone turnover in overweight adolescents

J Adolesc Health. 2009 Jul;45(1):33-9. doi: 10.1016/j.jadohealth.2008.12.020. Epub 2009 Apr 25.

Abstract

Purpose: To examine the relationships between cognitive eating restraint and both bone mineral density (BMD) and markers of bone turnover in overweight adolescents.

Methods: One hundred thirty-seven overweight (BMI 39.1 +/- 6.8 kg/m(2)) African American and Caucasian adolescent (age = 14.4 +/- 1.4 years) girls (66.4%) and boys were administered the Eating Disorder Examination (EDE) interview and Eating Inventory (EI) questionnaire and underwent dual energy X-ray absorptiometry (DXA) to measure total lumbar spine BMD. Markers of bone formation (serum bone specific alkaline phosphatase and osteocalcin), bone resorption (24-hour urine N-telopeptides), and stress (urine free cortisol) were measured.

Results: After accounting for the contribution of demographics, height, weight, serum 25-hydroxyvitamin D, and depressive symptoms, adolescents' weight concern, as assessed by interview, was a significant contributor to the model of urine free cortisol (beta = .30, p < .05). Shape concern, as also assessed by interview, was significantly associated with lumbar spine bone mineral density (beta = -.15, p < .05). Dietary restraint was not a significant predictor in any of these models.

Conclusions: These findings suggest that among severely overweight adolescents, dissatisfaction with shape and weight may be salient stressors. Future research is required to illuminate the relationship between bone health and disordered-eating attitudes in overweight adolescents.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, N.I.H., Intramural

MeSH terms

  • Absorptiometry, Photon
  • Adolescent
  • Attitude to Health*
  • Biomarkers
  • Bone Density*
  • Bone and Bones / metabolism*
  • Child
  • Collagen Type I / urine
  • Feeding and Eating Disorders / psychology*
  • Female
  • Humans
  • Hydrocortisone / urine
  • Interviews as Topic
  • Lumbar Vertebrae / diagnostic imaging
  • Male
  • Overweight / physiopathology*
  • Peptides / urine
  • Surveys and Questionnaires

Substances

  • Biomarkers
  • Collagen Type I
  • Peptides
  • collagen type I trimeric cross-linked peptide
  • Hydrocortisone