Influences of cross-border mobility on tuberculosis diagnoses and treatment interruption among injection drug users in Tijuana, Mexico

Am J Public Health. 2009 Aug;99(8):1491-5. doi: 10.2105/AJPH.2008.142166. Epub 2009 Jun 18.

Abstract

Objectives: We sought to identify correlates of reported lifetime diagnoses of TB among injection drug users in the border city of Tijuana, Mexico.

Methods: Injection drug users in Tijuana were recruited into a prospective cohort study during 2006 and 2007. We used weighted multivariate logistic regression to identify correlates of TB diagnoses.

Results: Of the 1056 participants, 103 (9.8%) reported a history of TB, among whom 93% received anti-TB medication and 80% were diagnosed in the United States. Treatment was prematurely halted among 8% of patients; deportation from the United States was the cause of half of these treatment interruptions. History of travel to (odds ratio [OR] = 6.44; 95% confidence interval [CI] = 1.53, 27.20) or deportation from (OR = 1.83; 95% CI = 1.07, 3.12) the United States and incarceration (OR = 2.20; 95% CI = 1.06, 4.58) were independently associated with a reported lifetime diagnosis of TB.

Conclusions: Mobility and migration are important factors in identifying and treating TB patients diagnosed in the US-Mexico border region. Strengthening capacity on both sides of the border to identify, monitor, and treat TB is a priority.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Antitubercular Agents / therapeutic use*
  • Catchment Area, Health
  • Cohort Studies
  • Cross-Sectional Studies
  • Emigrants and Immigrants / statistics & numerical data
  • Female
  • Humans
  • Male
  • Mexico / ethnology
  • Population Dynamics / statistics & numerical data*
  • Population Dynamics / trends*
  • Prevalence
  • Prospective Studies
  • Substance Abuse, Intravenous / epidemiology*
  • Tuberculosis* / diagnosis
  • Tuberculosis* / drug therapy
  • Tuberculosis* / ethnology
  • United States / epidemiology
  • Withholding Treatment / statistics & numerical data*

Substances

  • Antitubercular Agents