[Pathogenic diagnosis of an unexplained epidemic event of infectious diarrhea]

Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2008 Dec;22(6):461-3.
[Article in Chinese]

Abstract

Objective: To determine the pathogen of an unexplained epidemic event of infectious diarrhea by laboratory diagnosis of suspected cases samples.

Methods: 28 samples from 28 suspected cases (22 fecal samples, 3 vomitus samples, 3 anus swab samples) were tested for Norovirus by RT-PCR. Sequencing and phylogenetic analysis were acomplished of 5 positive samples.

Results: 160 of 5694 population were ill with an attack rate of 2.81%. The peak period was 7-9, March. 14 of 28 samples were tested Norovirus positive.Sequencing and phylogenetic analysis showed Norovirus type GII/4 was the causative agent and it had highest identity (97. 9%) with epidemic strain 2006b.

Conclusion: The epidemic event ofinfectious diarrhea were caused by GII/4 Norovirus strains.

Publication types

  • English Abstract

MeSH terms

  • Disease Outbreaks*
  • Dysentery / diagnosis*
  • Dysentery / epidemiology
  • Dysentery / genetics
  • Feces / virology*
  • Gastroenteritis / epidemiology*
  • Gastroenteritis / virology
  • Humans
  • Molecular Epidemiology
  • Norovirus / classification
  • Norovirus / genetics
  • Norovirus / isolation & purification*
  • Phylogeny
  • RNA, Viral / analysis
  • Reverse Transcriptase Polymerase Chain Reaction

Substances

  • RNA, Viral