The stromal derived factor-1\CXCR4 axis--a legitimate therapeutic target in multiple myeloma?

Leuk Lymphoma. 2009 Jul;50(7):1067-8. doi: 10.1080/10428190902991837.
No abstract available

Publication types

  • Comment

MeSH terms

  • Animals
  • Apoptosis
  • Bone Marrow Cells / metabolism
  • Cell Line, Tumor
  • Chemokine CXCL12 / metabolism*
  • Extracellular Matrix / metabolism
  • Gene Expression Regulation, Neoplastic
  • Hematopoietic Stem Cells / metabolism
  • Humans
  • Ligands
  • Matrix Metalloproteinase 9 / metabolism
  • Mice
  • Multiple Myeloma / drug therapy*
  • Multiple Myeloma / metabolism*
  • Receptors, CXCR4 / metabolism*

Substances

  • Chemokine CXCL12
  • Ligands
  • Receptors, CXCR4
  • Matrix Metalloproteinase 9